Introduction: Ventricular fibrillation and pulseless ventricular tachycardia are the arrhythmias that most frequently appear in sudden cardiac arrest in adults (more than 85%), the correct treatment is early electrical defibrillation. Objective: To determine the management of semi-automatic external defibrillators in nursing students. Guayaquil University. 2029-2020. Methodology: A descriptive, quantitative methodology was used, the sampling was non-probabilistic, by means of volunteer subjects, being made up of 146 students, using as an instrument a questionnaire made up of closed and open questions that were analyzed with the SPSS statistical package. Results: Only 28% recognize the paddle placement zone, 68.4% rarely check if the patient is urinated or wet and 57.5% rarely recognize that the paddles should not be placed on top of the pacemaker, 100% know that it is necessary to voice the alarm before performing the electric shock, among the main factors are 100% frequently the lack of DSA simulators in laboratories, followed by 71.9% who respond that they rarely handle the equipment during hospital practices and the lack of motivating methodologies representing 67.8%, strategies, with 100% enabling laboratories with adequate simulators, 97.9% improving the coverage for handling equipment during hospital practices, 93.8% using motivating methodologies. Conclusions: There are difficulties in handling defibrillators, mainly influenced by the lack of defibrillators in laboratories and the possibility of handling the equipment during hospital practice, together with the lack of motivational methodologies on the part of the teacher.