Introduction: the challenges of the agri-food sector have driven companies to look for different ways to improve their competitiveness, which has led to the emergence of industry 5.0. This new industrial era not only focuses on the implementation of advanced technology in supply chains, but also on fostering resilience, increasing sustainability and maintaining a human-centric approach at all stages. Aim: supply chains in agribusiness, taking into account the three essential pillars of industry 5.0. Methodology: the selection of indicators was carried out through a systematic literature review, using Fink's methodology. It covered 97 articles in English and Portuguese published between 2020 and 2024. The analysis of these documents was carried out using the Atlas.ti software version 2019, applying the 4W model (when, who, where and what) and answering the three research questions posed through the PICO strategy. Results: The results highlight an increase in the publication of articles starting in 2021, coinciding with the period after the highest peak of COVID-19 infections, when companies began to adapt to the new reality. During this period, companies sought ways to mitigate the impact of disruptive events on their productive and economic activities, identifying key factors of Industry 5.0 to apply in supply chains. Conclusions: the complete implementation of Industry 5.0 still faces difficulties. Although significant studies have been carried out on the subject in India, its application has been complicated. Finally, 21 possible indicators are proposed with their variables for agri-food chains, based on the three essential elements (sustainability, resilience and human focus) and eight key criteria derived from these elements. General study area: Production and Operations. Specific study area: Materials design and production. Type of study: bibliographic review