Factores asociados al desarrollo de resistencia al tratamiento: reporte de un caso

Abstract

Introduction. Multidrug-resistant tuberculosis is a threat to public health; despite the existence of treatment, it continues to be the infectious disease that causes the most deaths worldwide. Objective. To determine factors associated with multidrug-resistant tuberculosis through a clinical case from the El Paraíso Health Center in the city of Machala. Methodology. This is a 43-year-old male patient, mestizo race, no occupation, with a history of type II diabetes mellitus for 17 years, currently under regular treatment with intermediate-acting insulin 20 IU AM and 10 IU PMI, with poor control and not adhering to treatment, alcohol consumption 4 times per week, tobacco 2 packs per day, cocaine consumption 5 years ago for 6 months, presenting a clinical picture characterized by cough with mucopurulent expectoration, accompanied by weight loss, nocturnal thermal rise, asthenia and anorexia for approximately 1 month. He was diagnosed with treatment-resistant tuberculosis and started a second-line treatment regimen. Results. Patient with rifampicin-resistant tuberculosis with associated risk factors: drug addiction, alcoholism, chronic smoker, insulin-dependent type 2 diabetes, and high psychosocial risk.