Introduction: Hypothyroidism is a common endocrine disorder that results from thyroid hormone deficiency. The prevalence of overt hypothyroidism increases with age, with more than 10% of women older than 60 years having subclinical hypothyroidism. The main objective of this study was to evaluate the comparison of the morning versus evening dose of levothyroxine in the treatment of hypothyroidism. Methodology: 152 patients with previously untreated primary hypothyroidism were divided into morning (Group 1) and evening (Group 2) dosing groups and evaluated for change in biochemical profile, physical functioning, and quality of life over the course of twelve study weeks. Results: At the end of 12 weeks, 70 (90.90%) subjects from Group 1 and 72 (96%) from Group 2 reached euthyroidism. At evaluation, symptoms and total clinical prescriptions improved in both groups at the end of 6 and 12 weeks. A significant improvement in thyroid profile was demonstrated in both groups at the end of 6 and 12 weeks (P value <.0001). Conclusion: In the between-group comparison, no significant differences were observed in the thyroid profile at 6 and 12 weeks between the morning and evening dose groups. A similar dose of levothyroxine was required to achieve euthyroidism in both groups. Although early restoration of euthyroidism was reduced in the evening group, the difference compared to the morning group was not statistically significant. In the evaluation of the quality of life, a statistically significant improvement was demonstrated in several parameters in both groups. Therefore, we infer from the study that the evening dose is as effective as the morning dose and provides an alternative dosing regimen. Study area: Health Sciences.

Introduction: this research studies how educommunication and ICT considered within a communication project, aim to improve students' attitudes regarding environmental care.  Objectives: the objective is to identify the results obtained from the application of the survey aimed at students of the fiscal educational units of the city of Riobamba-Ecuador, referring to the digital and educommunicative tools used to promote environmental education.  Methodology: the study presents a quantitative approach, in which a survey aimed at the integrated population of students of the aforementioned educational units was used.  Results: the results show the tendency of respondents to incorporate ICT and educommunication as tools to analyze social responsibility and environmental awareness in teaching-learning processes.  Conclusions: it is necessary to establish environmental education programs in the classroom, which develop knowledge, skills and values that allow them to be aware of the world and its difficulties, that integrate the environment as a whole.  Area of study: communication.

Introduction. This article is based on the analysis of labor performance in masonry in housing in the city of Cuenca, which directly influences productivity and is a crucial part of the economy of a nation. The yields used in the budgets and programming of works, must be based on multiple observations and statistical analysis, in the companies dedicated to the construction many of the economic losses are affected by the human factor and many times they are not identified and quantified. Objective. To analyze the labor yields in masonry items in houses of up to two floors in the city of Cuenca, comparing the results with the information of the Chamber of Construction of Cuenca to generate strategies to improve performance. Methodology. This study was conducted in four stages: in the first stage, the collection of data and the calculation of labor performance in masonry items, in the second stage, the comparison and analysis of data with the Chamber of Construction of Cuenca, in the third stage, a literature review was conducted and a strategy was defined to improve labor performance in masonry items, in the fourth stage, recommendations of technical specifications and the correct masonry construction process are given. Results. Through the methodology applied, the results show that for the five masonry items under study: industrial brick, handmade brick, exposed brick, pumice block and mixed block (pumice-concrete), the labor yields are lower than those of the Cuenca Chamber of Construction, except for industrial brick. Conclusion. Labor yields are affected by some factors that negatively affect productivity, but by implementing the strategy of training construction workers, a significant improvement is expected.

Introduction: this research article is based on the elaboration of a methodology to know the citizen perception in the process of selecting a person in the Ecuadorian public sector. Objectives: to develop a methodological proposal that involves the citizen who was part of a personnel selection process in order to know the opinion of the participant after a selection process with the purpose of improving the selection process by the institution that carried it out. Methodology: the methodological proposal is a questionnaire whose information base was taken from the review of the technical standard of the personnel selection subsystem and this questionnaire is made up of 12 items that frame the personnel selection process from the call to selecting to the right person who has passed all the steps of the selection process. In this investigation, the Cronbach's Alpha calculation method was developed, which is a coefficient used to measure the reliability of a test and in which 45 people participated who responded to the survey carried out according to their personal experience during a personnel selection process in the that I participate Results: with the information that was obtained and through Cronbach's Alpha and a Likert analysis in each item, the developed questionnaire was validated, obtaining a score of 0.94. Conclusions: the tool has a high reliability also in the present investigation and it is proposed that at some point the tool may be useful for its implementation in human talent departments in public institutions and therefore improve the selection process. personnel and highlight possible shortcomings. Study area: Human Talent.

Introduction. Depression is the most common mental disorder among older adults and one of the most disabling conditions worldwide. Objective. To review the scientific evidence on the psychometric properties of the geriatric depression scale. Methodology. A documentary study of systematic literature review was carried out. Regarding the search strategies, we worked with the library of the Catholic University of Cuenca, the Scopus, PubMed and Web of Science databases were used, from 2017 to 2021in English and Spanish language.  This allowed obtaining a total of 14 articles that were thoroughly analyzed. Results. The Geriatric Depression Scale (GDS) has adequate, reliable, and valid psychometric properties to assess knowledge about geriatric depression, thus contributing for students, health profession, because it is a brief and easy to apply screening instrument, widely used in clinical and research to detect depressive symptoms in older adults that can provide a reliability of an adequate diagnosis. Conclusion. It is concluded that the GDS is a reliable instrument to apply in the older adult population.

Introduction: The Barthel index was taken as the central axis of research, with the intention of knowing its contributions to patient care, the adaptations in its psychometric properties made, weaknesses in the measurement, with the intention of clarifying the theoretical and methodological route for a possible adaptation and validation to the reality of Ecuador, where there is currently no direct research on the described. Objective: The objective was to review the scientific evidence on the psychometric properties of the Barthel index. Methodology: It was based on a systematic review of the scientific literature using the PRISMA procedure, taking the most significant contributions, based on 11 articles published in PubMed, WOS, Scopus. Results: The different articles used validate the Barthel index as a method to assess the physical capacity of patients who have suffered strokes. Conclusion: The Barthel index is shown to be a reliable instrument in the researches scrutinized, including the adaptations that have been made, being considerable to be taken into account by the nursing staff with the intention of promoting a care management in accordance with providing a diligent and quality service to the patient and his family.

Introduction: As there is no validation of MMSE for Ecuador, the elaboration of the current research becomes relevant because it is necessary to adapt, but for this it is necessary to know its international contributions. Objective: The objective was to review the scientific evidence on the psychometric properties of MMSE. Methodology: A systematic review was generated in the scientific literature from the PRISMA procedure, working with 10 articles published in various databases such as Scielo, PubMed, WOS, Scopus. Results: The scores obtained with the MMSE and the MoCA are related to each other; however, MoCA scores are lower and more dispersed in different age and schooling groups, so a different cut-off point could be used to determine MCI in the community population. Conclusion: Evidence from those who exclusively used MMSE, consider beneficial to achieve cognitive measurement goals. Regarding the adjustment rates of the Mini Mental State Examination, there is a variation in the criteria of the population where it is used, with considerable validation to be carried out in various contexts, which could contribute to increasing the effectiveness of the MMSE.

Introduction. Carpal tunnel syndrome is a neuropathy that occurs at the level of the median nerve located in the wrist, causing pressure and, consequently, a decrease in its function. Objective. To examine a systematic review on the applicability of the platelet-rich plasma technique in carpal tunnel syndrome. Methodology. Systematic review of the descriptive and explanatory literature, following the PRISMA statement and with the help of the Descriptors in Health Sciences (DECS). Results. Treatments for carpal tunnel syndrome can be conservative or surgical. Platelet-rich plasma is one of the most widely used due to its content for tissue regeneration. According to the reviewed literature, it has its benefits between three and six months after treatment. Another of the most used conservative treatments is the splint and the splint plus PRP, where it was observed through the analog variables and the Boston scale that this symptomatology decreased significantly in both groups after 10 weeks of treatment. Conclusions. Platelet-rich plasma is a less invasive treatment that produces less pain in its application, requires less time, does not require hospitalization, and improves the discomfort of carpal tunnel syndrome.

Introduction. Diabetic foot is defined as infection, ulceration or destruction of the deep tissues of the foot that may be associated with different factors. Objective.  To carry out a bibliographic analysis and treatment of the disease to determine the risk factors of diabetic foot in elderly women through a clinical case of the FUNPRA geriatric center in the city of Cañar - Ecuador. Methodology. 80-year-old female patient, widowed, from the city of Azogues and resident in Cañar-Ecuador FUNPRA (nursing home), with no education. She is treated for diabetic foot grade I superficial wound in the right foot, does not involve tendon capsule or bone, in the healing process granulation tissue is observed. Results.  She was administered a general diet, physical activity prior to healing, insulin in the morning 14 IU/dL and in the afternoon 6 IU/dL per day at the end of healing and bandaging. With 3 years of evolution DMT type II, 3 months of evolution of diabetic foot. No pathological, surgical or family history. Improvement of the patient is observed after the cures performed, control of glycemia and administration of medication appropriately. Conclusion.  A patient with diabetes mellitus type II was treated, her diabetic foot was associated with obesity, inadequate care and poor hygiene.

Introduction. At present, there are few studies on placentophagy in animals and the benefits that could be derived from the consumption of placentomas, whether of the same species or of a different one. Objective. The objective of this research is to evaluate the effect of bovine placentomas in the treatment of iron deficiency anemia in dogs. The study was carried out in the city of Guayaquil. Materials and methods. The placentomas were extracted from the slaughtering center of the city of Guayaquil, being cooked completely at a temperature of 160° Fahrenheit and then dehydrated for 8 hours, to pulverize them and proceed to encapsulate them and supply them to an experimental group of dogs (group A), while the control group (group B), was supplied with multivitamin tablets existing in the market, which contained trace elements such as iron in their composition. Results.  The results obtained in this research were that 60% of the animals that were supplied with placentomas got rid of their iron deficiency amenia. Conclusions. It was demonstrated that the consumption of placentomas does have favorable effects in patients with iron deficiency anemia.