Endothelial dysfunction in cardiometabolic health

Abstract

Introduction: cardiometabolic diseases are one of the main causes of death of people worldwide and endothelial dysfunction interrupts the permeability of the endothelial barrier that is part of the inflammatory response in their development. As such, suppression of endothelial cell activation and inflammation has clinical relevance, promoting this group of degenerative diseases. Objective: to expose the generalities of the endothelium and the association of its dysfunction with some of the main cardiometabolic diseases addressed in the first level of care. Methodology: narrative review of the literature that included fifty-two articles selected based on their open availability and being published in English and Spanish. Conclusion: the endothelium, as an active cell in the inflammation process - including silent or low-grade inflammation - constitutes a target of in-depth study by health professionals who work with cardiometabolic patients, the approach directed at it and its Pro and anti-inflammatory products, in the not-too-distant future, could increase even more in the context of medical treatment and cardiometabolic prevention.