Pneumonia due to ampicillin-resistant Haemophilus Influenzae in a patient with COPD

Abstract

Haemophilus influenzae is a gram-negative coconut bacillus that has the capacity to produce different serious and invasive colonizations including respiratory infections. When a patient presents risk factors such as chronic pathologies, mainly chronic obstructive pulmonary disease, the association of pneumonia occurs frequently, the latter being an acute infection of the pulmonary parenchyma that affects hospitalized patients or not and that is characterized by the appearance of fever and / or respiratory symptoms, together with the presence of pulmonary infiltrates on the chest radiograph. Its confirmatory diagnosis requires the isolation of the microorganism and the treatment of first choice to counteract the effects of this microorganism are beta-lactam antibiotics, which are less and less efficient, due to the resistance mechanisms of H. influenzae. We present the case of a 68-year-old male patient with a history of COPD who was treated at the San Gregorio Clinic for a 48-hour picture of the evolution of thermal rises and a nighttime cough concomitantly with the chills, profuse diaphoresis and malaise general. Antibiotic therapy begins with poor clinical response at 72h, cultures are received, antimicrobial resistance to ampicillin is identified, antibiotic rotates, favorable clinical evolution is observed.