Analgesic pharmacological treatment of renal colic

Abstract

Introduction: Nephritic colic is a painful episode of great intensity and acute onset, which after subsidence can experience intermittent relapses, frequently associated with nephrolithiasis, being the analgesic drugs used for the management of these patients. Objective: To compare the efficacy of the most used analgesic pharmacological treatments in the approach to nephritic colic due to nephrolithiasis. Methods: A systematic literature search was performed in PubMed, ScienceDirect, Redalyc and LILACS, using the search algorithm such as "pain" [MeSH Terms] OR "pain" [All Fields]) AND ("nephrolithiasis" [MeSH Terms] A total of 65 potential results were obtained, to then limit the study to 12 articles based on the criteria of the number of participants previously exposed, and the availability of the full text for free. Results: Among the analgesic drugs used for renal colic due to nephrolithiasis, it was demonstrated that the effect of NSAIDs, intravenous lidocaine, hydromorphine, even combinations such as ketorolac + isotonic saline can control general abdominal pain and pain due to nephrolithiasis. Conclusions: Among the included studies, it was found that IV ibuprofen and IM diclofenac are even more effective than IV paracetamol or IV morphine, with the administration of diclofenac for renal colic pain showing greater advantage and being preferred by patients. patients.