Introduction. This research proposes a comprehensive analysis of deaths considered natural using the Forensic Information Management System (SIGIF) and the National System of Legal Medicine and Forensic Sciences (SNMLCF) in Zones 1 and 2 in the year 2024. The aim is to define the classification of cases that can be classified as violent according to the Comprehensive Organic Penal Code (COIP), thus providing valuable information to the wider community. With the aim of determining the classification of cases that could be reclassified as violent, as indicated by the Comprehensive Organic Criminal Code (COIP), thus providing valuable information for the community at large. Methodology. A quantitative and qualitative approach was used to analyze the 2024 database, identifying the reclassification rate and associated factors. The combination of methods provides clarity in addressing the research question, also considering the analytical method. Results. In this challenge, a qualitative, quantitative, and analytical analysis was conducted on the initial DINASED database, issued by SIGIF and SNMLC 2024. After a rigorous analysis, the results of this research, which records natural deaths admitted to the morgue due to numerous factors, were concluded to be important. These results are useful for organizing and strengthening the reclassification of forensic research, which allows for more effective and secure public policy design. Conclusion. There are underlying factors that justify forensic intervention, considering the COIP's focus on violent deaths. Therefore, reclassification is a key factor in the investigation. It allowed for the identification of risks of error and the formulation of recommendations to optimize the classification processes for natural deaths in the morgue. However, the lack of valid clinical documentation highlights the need to strengthen communication between health services and the Prosecutor's Office to optimize forensic management. General Area of Study: Health. Specific area of study: Forensic Sciences. Type of study: Original articles.

Introduction: Population aging is a global phenomenon that, in Ecuador, reflects a marked feminization, with a higher proportion of elderly women. Objective: Analyze the feminization of aging in Ecuador by exploring differences in life expectancy and quality of life between men and women. Methodology: A comprehensive literature review was conducted using major scientific databases and search platforms, such as PubMed, Google Scholar, Scopus, and ResearchGate. Results: Women have a longer life expectancy and at the same time face more challenges than men, including a higher prevalence of chronic diseases and conditions of psychosocial vulnerability. Conclusion: The literature review highlights the urgent need to develop public policies focused on improving the quality of life of older women, addressing both gender inequalities and the social and economic factors that affect their well-being in old age. General field of study: Medicine. Specific field of study: Geriatrics. Type of study: Systematic literature narrative.

Objective. To analyze the literature regarding enamel and dentin remineralization with biomimetic materials to understand their effectiveness and clinical applications. Methodology. Comprehensive research of scientific articles was conducted that included in vitro studies, systematic reviews, and meta-analyses published between 2019 and 2024. The databases consulted were Pubmed, Science Direct, and Springer Link and Google academic was used as a secondary search engine. Results. Despite all the promising studies, biomimetic strategies still face challenges in the field of dentistry. Conclusion. Biomimetic remineralization has evolved from an experimental concept to an emerging clinical reality, establishing P11-4 peptides, stabilized CPP-ACP dentifrices, and zinc-carbonate hydroxyapatite as viable therapeutic options for immediate implementation. The trend toward multifunctional materials combining remineralizing, antibacterial, and anti-adhesive properties represents a paradigmatic evolution that transcends traditional restorative approaches toward comprehensive tissue regeneration. Despite promising evidence, a critical gap persists between abundant laboratory research and limited clinical evidence requiring priority attention. Biomimetic remineralization possesses transformative potential to revolutionize preventive and therapeutic management of dental caries, transitioning toward a regenerative model that could significantly reduce the burden of oral disease at the population level. General Area of Study: Medicine. Specific area of study: Dentistry. Type of study: Systematic bibliographic review

Introduction: Genu valgum is a common orthopedic disorder in children that can affect their mobility and quality of life if not accurately diagnosed and treated. In Latin America, the lack of unified criteria and organized information makes its management difficult, especially in Ecuador, where there is no updated review of age-specific treatments. Given the growing concern about children's musculoskeletal health and the inequality in access to specialized care, it is essential to compile and analyze the available evidence to optimize diagnosis and treatment, improve clinical practice and patients' quality of life, and avoid unnecessary interventions. Objective: To analyze the scientific information available on the treatments used for genu valgum in the pediatric population, evaluating their efficacy according to the different ages, in research conducted in the last five years. Method: A theoretical review was conducted through the PICOT strategy: using DeCS/MeSH terms in relevant health databases such as PubMed, Scopus, Google Scholar, Web of Science and Springer Link. Specific search strategies will be applied using keywords and MeSH (Medical Subject Headings) terms to identify relevant primary studies such as “Genu valgum,” “Child,” “Treatment” accompanied by Boolean operators such as ‘AND’ and “OR.” Results: Its origins can be congenital, nutritional, biomechanical or postural. To evaluate it, measurements such as the thiofemoral angle, intermalleolar and intercondylar distances, and radiographs are used. Treatment varies from physiotherapy and corrective exercises to surgery in severe cases. The benefits of early therapeutic programs to improve posture and function are also highlighted. Furthermore, the psychosocial impact of genu valgum is highlighted, affecting the self-esteem and social interaction of the child or adolescent. Conclusions: genu valgum represents more than a physical alteration; it is an indication of the organism that suggests the need for clinical, preventive, and empathic intervention. This analysis helps to deepen the understanding of the situation and paves the way for new therapeutic options, adapted and focused on the well-being of the child being in continuous evolution. General Area of Study: Medicine. Specific area of study: Pediatric Traumatology and Orthopedics. Type of study: Bibliographic review.

Introduction: Enterococcus faecalis is one of the main microorganisms associated with endodontic treatment failures due to its ability to form biofilms, survive in harsh conditions, and exhibit antimicrobial resistance, particularly to vancomycin. In response to this clinical challenge, the Triple Antibiotic Paste (TAP), composed of ciprofloxacin, metronidazole, and minocycline, has shown promising results due to its synergistic antibacterial activity against persistent bacteria in root canal systems. Objective: To evaluate the antibacterial efficacy of triple antibiotic, paste against resistant strains of Enterococcus faecalis through an exhaustive review. Methodology: An exhaustive review was conducted following the PRISMA guidelines. A total of 138 scientific articles were identified and analyzed from indexed databases (PubMed, Scopus, and ScienceDirect), using MeSH and DeCS descriptors combined with Boolean operators AND/OR. Results: Most included studies demonstrated that TAP exhibits high antimicrobial effectiveness against E. faecalis, including strains resistant to conventional antibiotics. Both in vitro and vivo investigations revealed a significant reduction in bacterial load and disruption of radicular biofilms, outperforming other intracanal medications such as calcium hydroxide and chlorhexidine. Conclusions: Triple antibiotic paste is an effective therapeutic option in regenerative endodontics and retreatment procedures, particularly in persistent infections caused by Enterococcus faecalis. Its rational and standardized use can improve clinical outcomes in complex cases, making it a relevant tool in managing antimicrobial resistance within the root canal system. General area of study: Health Sciences. Specific area: Dentistry. Study type: Literature review.

Introduction. Bone exostosis is a benign, multifactorial lesion that appears in various locations, sizes, and shapes. Despite being harmless, it may be a problem for patients with prosthetic needs. Objective. Analyze treatment options for patients with osseous exostoses requiring prosthetic care. Determine surgical considerations for managing maxillary or mandibular exostoses in prosthetic rehabilitation. Evaluate factors influencing the choice of prosthetic treatment in patients with exostoses. Methodology. A descriptive cross-sectional study was conducted using PubMed, Google Scholar, Scopus, and Cochrane to find relevant studies addressing prosthetic complications of OE. Results. A total of 34 articles were reviewed, offering alternatives to improve the quality of life in patients with prosthetic needs. Conclusion. Treatment should be individualized according to each patient’s clinical condition and specific needs. General Area of Study: Dentistry. Specific area of study: Oral Surgery, Prosthodontics. Type of study: Bibliography Review.

Introduction. Orthognathic surgery is a surgical procedure used to correct deformations and asymmetries of the maxillo-mandibular complex, especially in those in which there are occlusal alterations. The surgeon and orthodontist intervene to obtain occlusal stability, facial harmony, correct bone discrepancies and improve basic functions such as chewing, phonation and breathing. The most common skeletal malocclusion in which orthognathic surgery is usually performed is Class III, which in turn is distinguished by 1) mandibular prognathism, 2) maxillary retrognathism or 3) a combination of both characteristics. Conventional treatment planning consists of three phases: pre-surgical orthodontics, orthognathic surgery and post-surgical orthodontics. The Surgery First technique, because when it is performed on indicated patients, offers advantages such as shorter treatment time, lower cost, improvement of the facial profile by correcting skeletal bases, orthodontic decompensation is effective due to the phenomenon of regional acceleration and rapid recovery of the patient. Objective.  The objective of this research is to demonstrate, through a literature review, the effectiveness of the Surgery First technique prior to orthodontic treatment in patients with class III malocclusion, comparing the effectiveness in reducing the treatment time of the technique in relation to the conventional orthognathic surgical technique. Methodology.  This research work is a descriptive bibliographic and documentary review of the use of the orthognathic surgery technique called Surgery First prior to orthodontic treatment in patients with Class III skeletal malocclusion. It was developed under the indications PRISMA (Prerrefered Reporting Items for Systemic Reviews and Meta-Analysis). Results. The surgery technique first shortens the treatment time and produces aesthetic changes instantly. Unlike the conventional orthognathic technique, which comprises 3 phases, a pre-orthodontic of approximately 12-18 months, the surgery itself and a post-surgical orthodontic phase with an estimated time of 5 to 12 months. With Surgery First, tooth movement is accelerated thanks to previous surgery, so it takes 10 months of post-orthodontics and the total treatment time decreases. Conclusion. In this work, the effectiveness of Surgery First in reducing the total treatment time compared to the conventional technique has been analyzed. It was concluded that the protocol used in SF is effective and requires less time, it is estimated that an average of ten to twelve months less than the conventional technique. Therefore, the treatment time for FS could be approximately fifteen months, while the conventional protocol has an estimated time of two years. General area of study: Dentistry. Specific area of study: Oral surgery, maxillofacial surgery, orthodontics. Type of study: Original articles.