Breast primary extranodal non Hodgkin lymphoma, about a case

Abstract

Introduction: Breast primary non-Hodgkin lymphoma is an infrequent entity, is less than the 0,5% of all the malignancies of the breast. Due the lack of specific characteristics, clinics or by image (mammogram and ultrasound), it is difficult to stablished a pre surgical diagnoses, confused it with breast carcinoma, that could even occur with the cytological and histologic diagnosis using any of the current pathology methods. Immunohistochemistry is required to corroborate the diagnosis, type its cell of origin and select and adequate and more precise treatments. Objective: To explain the clinical and pathological characteristics of the primary extranodal NHL of the breast through the presentation of a case. Methodology: A review of the literature related to the subject was carried out and this review was prepared, the exposed case was diagnosed and treated at the Faustino Pérez Hospital in Matanzas, Cuba. Results: We present a case of a Breast primary extranodal non-Hodgkin lymphoma in a patient of 66 years old that shows a bad outcome, being deceased at the time of this report. Conclusions: it is a rare entity, with an unfavorable prognosis. There is a lack of clinical, diagnostic or therapeutic guidelines that allow optimizing the diagnosis and immunohistochemistry is essential to filiate the type of lymphoma and to be able to propose a treatment with immunotherapy.