Metabolic clinical profile in latent autoimmune diabetes in adults: considerations from primary care

Abstract

Introduction: LADA type diabetes was originally identified in 1977 by Irvine WJ et al. However, it was not until 1993 that Toumi et al introduced the term for the first time. Currently there is no consensus to define exactly LADA, thus, LADA diabetes is a form of type 1 diabetes of slow progression that is characterized by presenting manifestations classically associated with type 2 diabetes, plus evidence of antibodies against b-cells. pancreatic, particularly autoantibodies against glutamic acid decarboxylase. Objective: Synthesize the main considerations of LADA type diabetes from the perspective of primary care. Methodology: bibliographic review of articles and books published in the PubMed, ScienceDirect and ScieElo databases. In the non-systematic search, the LADA terms and descriptors were used; Latent autoimmune diabetes in adults; and Latent autoimmune diabetes in adults; The inclusion criteria were used: seniority no more than 5 years, Spanish or English language, including the topics pathophysiology, epidemiology, pathogenesis, etiology, clinical characteristics, diagnosis, comorbidities, treatment and approach from the first level - prevention; and be available for free. After applying the inclusion criteria, the search was reduced to 531 papers; of which thirty-five were selected from the quick reading. Results: a review of the literature was constructed that synthesizes the main aspects regarding LADA diabetes and guides elementary considerations for its suspicion and approach at the first level of health. Conclusion: LADA type diabetes is an underdiagnosed form of type 1 diabetes with a higher incidence than classic type 1 diabetes; suspecting it and managing it at the first level of care is a competence of primary care professionals, given its incidence, however, the diagnosis must be made by a specialist in the area.