Small Cell Carcinoma of the uterine cervix, about a case

Abstract

Introduction: Cervical cancer is one of the leading causes of cancer death among women. Neuroendocrine tumors are aggressive and develop from endocrine cells in various organs, including the female genital tract, and specifically the uterine cervix. Objective: to describe the clinical- epidemiological characteristics of small cell carcinoma. Methodology: we made a review of the bibliography on the subject and presented the results. Results: They account for 0.9%–1.5% of all tumors of the uterine cervix and generally affect women of reproductive age. Given the rarity of the disease, limited data are currently available regarding the biology, clinical behavior, and management of such aggressive tumors. The etiopathogenetic association between cervical small cell carcinoma (SCCC) and high- risk HPV infections has been well documented in some studies and has a much worse prognosis compared with other histological types of cervical carcinoma. The treatment modalities of SCCC and small-cell lung cancer are similar due to similar biological behavior. Chemotherapy is an important component of multimodal therapy. We made a case presentation of a patient with diagnosis of SCCC with an overall survival of six years, well above the average international survival. Conclusions: research should continue to reach consensus on the appropriate treatment.