Hematological alterations in patients with human immunodeficiency virus

Main Article Content

Santiago Pacheco Toro
Sandy Fierro Vasco
Juan Vega Vasco
Silvana Vega Vasco

Abstract

Infection with the Human Immunodeficiency Virus, HIV presents with a variety of hematological alterations and can be seen as a complication of the disease itself or linked to treatment. It is characterized by an ineffective erythropoiesis caused by opportunistic infections, malignancies and drugs. In this article we want to determine the most frequent hematological alterations that occur in patients with human immunodeficiency virus treated at the Enrique Garcés Hospital, located in Quito, Ecuador. A simple random sampling was performed for finite universe. The study is of a retrospective descriptive type of a series of cases in the Comprehensive Care Unit for HIV-AIDS patients at Enrique Garcés Hospital. The medical records of the patients treated in 2017 were reviewed. A sample of 105 patients was obtained. It was evidenced that the majority (86.7%) of the cases correspond to the male sex with an average age of 33 years. The prevalence of anemia was 13.3%. The women had a higher prevalence of anemia. Leukopenia was more frequent in the group of patients with CD4 values below 200 cells / μ. It is concluded that the prevalence of anemia was not very high, it prevailed in the female sex with a hypochromic normocytic pattern. Leukopenia was more frequent in the group of patients with CD4 values below 200 cells / μ. Platelets in most patients were in normal range.

Downloads

Download data is not yet available.

Article Details

How to Cite
Pacheco Toro, S., Fierro Vasco, S., Vega Vasco, J., & Vega Vasco, S. (2020). Hematological alterations in patients with human immunodeficiency virus. ConcienciaDigital, 3(1.1), 253-263. https://doi.org/10.33262/concienciadigital.v3i1.1.1145
Section
Artículos

References

1. Sloand E1.. Hematologic complications of HIV infection. AIDS Rev. 2005 Oct-Dec;7(4):187-96.
2. Opie J. Haematological complications of HIV infection.S Afr Med J 2012;102(6):465-468.
3. De Santi G, Menezes D. Hematological abnormalities in HIV-infected patients. International Journal of Infectious Diseases 15 (2011) e808–e811.
4. Mehta S . Jutur S. Gautam D. Hematologic Manifestations of HIV/AIDS. Medicine Update-2011; 483:490
5. Wilfred D. Magnitude and correlates of moderate to severe anemia among adult HIV patients receiving first line HAART in Northwestern Tanzania: a cross sectional clinic based study. Pan African Medical Journal. 2016; 23:26
6. Lai JL, Chen YH, Liu YM, Yuan J, Prevalence and risk factors of anemia in hospitalised HIV- infected patients in southeast China. Epidemiology Infected 2019, 235-242.
7. Wisaksana et al. Anemia and iron homeostasis in a cohort of HIVinfected patients in Indonesia BMC Infectious Diseases 2011, 11:213
8. Santiago-Rodríguez et al. Anemia in a cohort of HIV-infected Hispanics: prevalence, associated factors and impact on one-year mortalityBMC Research Notes 2014, 7:439
9. Pande A, Bhattacharyya M, Pain S, Ghosh B, Saha S, Ghosh A, Banerjee A. Anemia in Antiretroviral Naïve HIV/AIDS Patients: A Study from Eastern India. Online J Health Allied Scs. 2011;10(4):4
10. Meidani, et al.: Prevalence, severity, and related factors of Anemia in HIV/AIDS patients. Journal of Research in Medical Sciences 2012; 17(2): 138-42.
11. Freire W.B., Ramírez MJ., Belmont P., Mendieta MJ., Silva MK., Romero N., Sáenz K., Piñeiros P., Gómez LF., Monge R. 2013. Encuesta Nacional de Salud y Nutrición del Ecuador. ENSANUT-ECU 2011-2013 MSP.INECQuito, Ecuador.
12. Sanz K., Valores de referencia hematológicos en población alto andina ecuatoriana, empleando analizador SYSMEX XE-2100®* Rev Mex Patol Clin 2008; 55: 207-215.
13. Ogbe PJ1, Idoko OA, Evaluation of iron status in anemia of chronic disease among patients with HIV infection Clin Lab Sci. 2012 Winter;25(1):7-12.