Hepatoid carcinoma of the pancreas, case presentation

Abstract

Abstract Introduction: Hepatoid carcinoma of the pancreas (CHP) is extremely rare. It is a primary extrahepatic neoplasm that resembles hepatocellular carcinoma in terms of morphology and immunohistochemistry. In the pancreas, hepatoid carcinoma could be pure or mixed with other histological components such as neuroendocrine tumor or pancreatic ductal adenocarcinoma. Objective: to describe the clinical- epidemiological characteristics of hepatoid carcinoma of the pancreas. Methodology: we made a review of the bibliography on the subject and presented the results. Results: Induction of hepatocytes in the pancreas has been performed in several animal models. A case is presented at our stately institution T3 N0 M1, Clinical Stage IV, which received oncospecific treatment with chemotherapy, GEMOX scheme (12 cycles), with good tumor response, which at 6 months is revalued with CT that shows moderate ascites, second-line treatment with Gramont scheme (6 cycles) is decided according to response. Conclusions: it is a rare entity whose management is based on chemotherapy.