https://cienciadigital.org/revistacienciadigital2/index.php/AnatomiaDigital/issue/feed Anatomía Digital 2025-07-02T15:18:07+00:00 Dr.C. Efraín Velasteguí López PhD. luisefrainvelastegui@cienciadigital.org Open Journal Systems <div id="inicio"> <p>The <strong>Anatomía Digital</strong> journal promotes research in medical science and health in general. It is published quarterly, uninterruptedly, and publishes scientific manuscripts and communications on clinical, educational and scientific aspects.</p> </div> <div class="additional_content"> <div class="container" style="width: 100%;"> <div class="row2"> <div class="aimcolumn aimleft"><img style="width: 140%;" src="/revistacienciadigital2/public/site/images/diego91/find-a-provider.png"></div> <div class="aimcolumn aimright"> <div class="journal-description"> <p>The<strong> Anatomía Digital</strong> journal promotes research in medical science and health in general. It is published quarterly, uninterruptedly, and publishes scientific manuscripts and communications on clinical, educational and scientific aspects.</p> </div> <ul> <li class="show"><strong>Editor in Chief:</strong>DrC. Efraín Velasteguí López PhD</li> <li class="show"><strong>ISSN (online)</strong>: 2697-3391</li> <li class="show"><strong>Frequency:</strong>Quarterly</li> <li class="show"><strong>SJIF Journal Impact Value:</strong>[<a href="http://sjifactor.com/passport.php?id=22202">SJIF 2020 = 5.711</a>]</li> </ul> <div>&nbsp;</div> <div><a href="https://scholar.google.es/scholar?hl=es&amp;as_sdt=0%2C5&amp;q=2697-3391&amp;btnG=" target="_blank" rel="noopener"><img class="zoom2" src="/revistacienciadigital2/public/site/images/diego91/google-scholar-png.png" width="130" height="37"></a> <a href="https://www.base-search.net/Search/Results?type=all&amp;lookfor=Anatomia+Digital&amp;ling=1&amp;oaboost=1&amp;name=&amp;thes=&amp;refid=dcreses&amp;newsearch=1" target="_blank" rel="noopener"><img class="zoom2" src="/revistacienciadigital2/public/site/images/diego91/base_logo_kl.png" width="101" height="39"></a> &nbsp; &nbsp; <a href="https://search.crossref.org/?q=Anatomia+Digital&amp;from_ui=yes" target="_blank" rel="noopener"><img class="zoom2" src="/revistacienciadigital2/public/site/images/diego91/crossref.png" width="95" height="43"></a></div> </div> </div> </div> <section id="what-we-do"> <div class="container-fluid2"> <h1>Why publish with us?</h1> <div class="row2 mt-5"> <div class="col"> <div class="card"> <div class="card-block block-1"> <h3>Open Access</h3> <p>Anatomía Digital is a strong supporter of open access (OA). 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Periodical publications.</p> <a class="read-more" title="Read more" href="https://cienciadigital.org/revistacienciadigital2/index.php/AnatomiaDigital/indexa" target="_blank" rel="noopener">Read more<em class="fa fa-angle-double-right ml-2"><!-- icon --></em></a></div> </div> </div> <div class="col"> <div class="card"> <div class="card-block block-4"> <h3>No Payment</h3> <p>Digital Anatomy accepts original research articles and does not charge a publication fee.</p> <a class="read-more" title="Read more" href="https://cienciadigital.org/revistacienciadigital2/index.php/AnatomiaDigital/about/submissions" target="_blank" rel="noopener">Read more<em class="fa fa-angle-double-right ml-2"><!-- icon --></em></a></div> </div> </div> </div> </div> </section> </div> https://cienciadigital.org/revistacienciadigital2/index.php/AnatomiaDigital/article/view/3421 Epidemiology of Methicillin-Resistant Staphylococcus aureus with a “One Health” Approach 2025-07-02T15:18:07+00:00 Jeremy Leonel Sangucho Suntasig jsangucho2593@uta.edu.ec Ana Rafaela Burgos Mayorga ar.burgos@uta.edu.ec Sandra Margarita Cruz Quintana sm.cruz@uta.edu.ec Evelyn Katherine Jaramillo Ruales ek.jaramillo@uta.edu.ec <p><strong>Introduction. </strong>Methicillin-resistant <em>Staphylococcus aureus</em> (<em>MRSA</em>) represents a significant threat to public health due to its capacity for dissemination, colonization, and resistance to multiple antibiotics. Its distribution among humans, animals, food, and environment emphasizes the need to address it from a “One Health” approach. <strong>Objective. </strong>To analyze the epidemiology of methicillin-resistant Staphylococcus aureus, including its virulence profile, distribution in different reservoirs, frequency of resistance genes and evaluation of the susceptibility profile. <strong>Methodology. </strong>A literature review was performed in PubMed, Scopus, and BVS databases, using MeSH terms and Boolean operators, applying the PRISMA method for article selection. <strong>Results. </strong>Analysis of 26 <em>MRSA</em>-focused studies identified the most prevalent virulence factors as: <em>nuc</em>, <em>hla</em>, <em>hlb</em>, <em>clfA</em>, <em>clfB</em>, <em>coa</em>, <em>ica</em>, and <em>icaD</em>, in addition to enterotoxins <em>seb</em>, <em>sel</em>, <em>seo</em>, and immunomodulatory genes <em>scn</em>, <em>sak</em>, and <em>chp</em>. The highest MRSA prevalence was identified in animal reservoirs (22.8%), followed by human (18.8%), food (7.7%), and environmental samples (4.6%). A high prevalence of the <em>mecA</em> (57.1%) and <em>blaZ</em> (70.7%) genes was observed, whereas the <em>mecC</em> gene was detected at a lower frequency (2.5%). Resistance to cefoxitin, oxacillin, penicillin, and ampicillin was consistently high across all reservoirs. Notably, resistance to vancomycin was detected in animal-derived isolates, representing a significant concern. Nevertheless, linezolid remained highly effective, with negligible resistance observed in the studied reservoirs. <strong>Conclusion. </strong>Methicillin-resistant <em>Staphylococcus aureus</em> exhibits a broad range of virulence factors and resistance determinants, with considerable prevalence across multiple reservoirs, highlighting its zoonotic potential and the importance of integrated surveillance within a One Health framework. <strong>General Area of Study: </strong>Health. <strong>Specific area of study: </strong>Microbiology. <strong>Type of study:</strong> Systematic bibliographic review.</p> 2025-07-02T00:00:00+00:00 Copyright (c) 2025 Anatomía Digital