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 Cesárea Electiva como Factor de Riesgo Asociado al Síndrome de Distress Respirator= io Neonatal

 

 

 

Elective Cesarean Section as a Risk Factor Associated with Neonatal Respiratory Dist= ress Syndrome

 

Diana Mishelle Moncayo Rivera [1], = Christian Miguel Moncayo Rivera . [2],<= /span> Justa María Serpa Calderón. <= /span>[3] & Nelson Ricardo Chacha = Suscal. [4]

 

 

Recibido: 17-09-2020  / Revisado: 10-11-2020 /Aceptado: 30-11-2020  / Publicado: 02-01-202= 1

 

DOI: https://doi.o= rg/10.33262/anatomiadigital.v4i1.1561

 

Abstract

Foundations: Elective Cesarean section is a surgical procedure that has increased worldwide in recent years. Respiratory morbidities are= the most frequent complications in neonates born in this way, especially due = to the absence of labor.

Objective: To determine, from a systematic literature revie= w, elective cesarean section as a risk factor for respiratory distress morbi= dity and mortality in newborns.

Methods: Fourteen articles were included on this topic th= at met certain inclusion criteria. The search was carried out in different journals such as Scielo, Cochrane, Medwave, Redalyc, PubMed, among others, published in the last 5 years, in English and Spanish language. Mendeley software was used to organize the information. <= /p>

Results: Developing countries have rates of the elective cesarean section above 40%, especially in the private sector. Neonatal re= spiratory morbidity-mortality increases by elective cesarean section being up to 3 times higher compared to vaginal delivery. Transient Tachypnea of the New= born was the most frequent entity of Neonatal Respiratory Distress Syndrome.

Conclusions: Elective cesarean section is a problem in underdeveloped countries because it brings with it important fetal compli= cations such as Transient Tachypnea of the Newborn, a pathology that can be prevented: firstly by properly educating the mother, adopting measures su= ch as premature labor in patients with a history of previous cesarean sectio= n, the use of antenatal steroids and the administration of oxytocin.

Keywords: respiratory distress, elective cesarean section, neonate, Transient Tachypnea of the Newborn

 

 =

 

Resumen

Fundamentos: La cesárea electiva e= s un procedimiento quirúrgico que ha incrementado en todo el mundo en los úl= timos años. Las morbilidades respiratorias constituyen las complicaciones más frecuentes en neonatos nacidos por esta vía, en especial por la ausencia= de trabajo de parto.

Objetivo: Determinar, a partir = de una revisión bibliográfica sistemática, la cesárea electiva como fact= or de riesgo para la morbi-mortalidad por distress respiratorio en recién nacidos= .

Métodos: se incluyeron 14 artículos en relación a este tema los cuales cumplieron determ= inados criterios de inclusión. La búsqueda se realizó en diferentes revistas = como Scielo, Cochrane, Medwave, Redalyc, PubMed, entre otros, publicadas en los últimos 5 años, en idioma inglés y español. Se empleó el software Me= ndeley para la organización de la información.

Resultados: los países subdesarrollados presentan tasas de cesáreas electivas superiores al 40%= , en especial en el sector privado. La morbi-mortalidad respiratoria neonatal aumenta por cesárea electiva siendo hasta 3 veces superior a comparació= n del parto vaginal. La Taquipnea Transitoria del Recién Nacido fue la entidad= más frecuente del Síndrome de Distress Respiratorio Neonatal.

Conclusiones: la cesárea electiva constituye una problemática en países subdesarrollados ya que trae cons= igo complicaciones fetales importantes como la Taquipnea Transitoria del Reci= én Nacido, patología que se puede prevenir: en primera instancia educando adecuadamente a la madre, la adopción de medidas como el trabajo de part= o previo en pacientes con antecedentes de cesárea anterior, el uso de corticoides antenatales y la administración de oxitocina.

Palabras Clave: Distress Respiratorio, Cesárea Electiva, Neonat= o, Taquipnea Transitoria del Recién Nacido.

Introducción

La OrganizaciÃ= ³n Mundial de la Salud (OMS), recomienda que la tasa de nacimientos por cesár= ea en un país debe encontrarse entre el 5 y 15% del total (Martínez, 2015), pero en América Latina para el año 2016, se incrementó hasta un 38.9% (Bernal, 2018).

Aquello indica= que ha ocurrido un aumento desproporcionado de cesáreas que probablemente no s= on necesarias, realizadas sin indicación médica y propuestas a las pacientes= como forma de parto más seguro, es decir, un reemplazo del proceso natural del nacimiento por una intervención quirúrgica  (Molina, 2019).

Las morbilidad= es respiratorias se informan como las complicaciones más frecuentes asociadas= con los partos por cesárea. En un estudio realizado en el Hospital Universitar= io de Guayaquil efectuado en el año 2015, Hidalgo concluye que el 73% de neonatos nacidos por cesárea programada presentó Síndrome = de Distress Respiratorio.

Esta patologí= a se define como los síntomas clínicos de la dificultad respiratoria neonatal temprana con características radiológicas de tórax consistentes y que ad= emás requiere suplementación de oxígeno dentro de las 24 horas posteriores al nacimiento para mantener una saturación de oxígeno óptima. Continúa sie= ndo la causa principal de mortalidad y morbilidad tempranas durante la infancia y = la niñez, que afecta aproximadamente al 1% de los recién nacidos (Li et al., 2019).

El riesgo de sufrir Distrés Respiratorio guarda estrecha relación con la vía de parto. El motivo resi= de durante el inicio del trabajo de parto: el feto sufre una situación de est= rés ya que sus pulmones intentan expulsar el líquido residual por su boca para llevar a cabo la primera respiración lo cual se ve favorecido por las contracciones uterinas y los movimientos realizados por el feto en el canal vaginal; al no existir este mecanismo en las cesáreas programadas la susceptibilidad de presentar complicaciones respiratorias incrementa hasta cuatro veces más un recién nacido a comparación del parto vaginal. AdemÃ= ¡s, el riesgo aumenta alrededor de 1,5 veces por cada semana si la cirugía ocurre antes de las 39 semanas de gestación.

Este estudio se plantea con el objetivo de determinar, a través de la comparación de múltiples estudios científicos, el parto por cesárea electiva como factor de riesgo para la = morbi – mortalidad por distrés respiratorio en recién nacidos, de tal manera = se podrá conocer la frecuencia, identificar la asociación estadística entre cesárea electiva (el factor de riesgo de estudio) y el distrés respiratorio y las principales patologías asociadas al mismo.

Por esta razón se pretende revertir dicho incremento, para de tal manera disminuir el índice de frecu= encia de la operación cesárea tanto en el sector público como en el privado, b= ajo indicación médica de forma indispensable, obteniendo como consiguiente me= nor costo a nivel hospitalario, una mejor atención en el trabajo de parto de l= a gestante y, por lo tanto, mejor beneficio materno-fetal (& Wolfman, 2015).

 

Metodologia=

Diseño: Se realizó una revisión sistemática de fuentes bibliográficas que realizaron el estudio: “CESÃREA ELECTIVA COMO FACTOR= DE RIESGO ASOCIADO AL SÃNDROME DE DISTRESS RESPIRATORIO NEONATALâ€. Para la localización de la información se emplearon palabras claves como Distrés Respiratorio, Cesárea Electiva, Neonato, Evidencia Científica, Labor de P= arto, Parto Vaginal.

Estrategia de Búsqueda: se efectuó una búsqueda general en la Biblioteca Virtual de la Universidad Católica de Cuenca y en Google Acadé= mico lo cual arrojó alrededor de 2152 resultados 2101 y 51 respectivamente, que incluían revistas científicas de distintos sitios web en Ecuador y a nivel internacional empleando palabras claves como Distrés Respiratorio, Cesárea Electiva, Neonato, Evidencia Científica, Labor de Parto, Parto Vaginal.

Posteriormente= se ejecutó una exploración en la base de datos de Scielo, PubMed, Medline, Cochrane, Elsevier, entre otros, para la obtención documentos que incluyer= on las palabras claves antes mencionadas y sus combinaciones, con publicacione= s de los últimos 5 años en idiomas como español e inglés excluyendo 2040; 61 documentos fueron sometidos a lectura de texto completo.<= /p>

Tras la lectur= a se excluyeron 47, incluyendo finalmente 14 documentos. Lo antes descrito se re= sume en el gráfico Nº1.

Criterios de Inclusión

Artículos que correspondieron en título y resumen, centrando a los conceptos de distrés respiratorio y partos por cesárea programada, cuyas publicaciones se reali= zaron entre los años 2015 al 2020 en idiomas de inglés y español.

Criterios de Exclusión

Se descartó todo aquel estudio que no presente re= sultados concluyentes, y que el análisis del estudio no estuvo regido al ámbito de= la investigación o que se aprecie la observación de otras profesiones que no= son coherentes acerca del contexto del parto por cesárea como factor de riesgo= del distrés respiratorio en neonatos.

Revisiones sistemáticas y artículos científicos relacionados con la cesárea electiva como factor de riesgo asociado al dis= trés respiratorio neonatal no correspondientes a los últimos cinco años.

Documentos redactados en idiomas distintos al ingl= és y español.

Organización de la información: Con ayuda del programa Mendeley, = se procedió a la selección de documentos de la literatura gris, revisiones sistemáticas, artículos científicos.

Se obtuvo en la búsqueda inicial alrededor de 2152 artículos, se excluyeron 2138 que no f= ueron relevantes para el objetivo de esta revisión, para finalmente seleccionar = 14 artículos.

Análisis de los datos: Una vez seleccionados los documen= tos científicos con ayuda del programa Mendeley se procedió a la extracción = de información sobre autoría, año, fuentes de información.

Resultados

La cesárea electiva es un procedimiento que se realiza de forma programada antes de un trabajo de parto verdadero realizado en gestantes con patologías en donde = no se recomiende un parto vaginal (Maternofetal, 2020; MSP, 2015).

Se ha visto un incremento masivo de cesáreas programadas en las últimas décadas, como e= s el caso del Reino Unido y Estados Unidos con porcentajes mayores al 30%, Brasil con más del 40% al igual que México, Paraguay y Ecuador , las cuales son = cifras alarmantes en comparación de la recomendación de la media 10% por país establecido por la Organización mundial de la Salud (Bernal, 2018).

Sin embargo, s= us ventajas no justifican su aumento continuo ya que conlleva considerables complicaciones respiratorias neonatales, en comparación con el parto vagin= al (Benzouina et al., 2016).

En el Hospital= de Ventanilla-Perú durante el año 2016, se comparó 197 neonatos nacidos por= parto vaginal y cesárea: 48,22% tuvieron Síndrome de Distrés Respiratorio Neon= atal (SDRN) de los cuales se encontró que aquellos nacidos por cesárea electiva tuvieron un porcentaje de 41,6, además se describieron como factores de ri= esgo el sexo masculino y macrosomía fetal (Trujillo Angeles, 2018). Similar resultado se obtuvo en el trabajo realizado por Bautista (2018) en el Hospital Vicente Corral Moscoso-Ecuador donde el porcentaje de distrés respiratorio en recién nacidos por cesárea electiva fue superior al 60%  , y su coterráneo Hidalgo (2015) en el Hospital Universitario de Guayaquil que describió 77 pacientes ingre= sados a la unidad de cuidados intensivos neonatales con diagnóstico de SDRN de l= os cuales el 73% nacieron por cesárea electiva. Por el contrario, Pirjani (2018) establece que no existe diferencia entre las complicaciones neonatales frecuentes como sepsis neonatal o SDRN

El mecanismo principal de las complicaciones respiratorias en los neonatos nacidos por cesárea programada reside en la ausencia de trabajo de parto; esto es, el líquido pulmonar residual que el feto intenta expulsar por su nariz y boca, dado por las contracciones uterinas y movimientos en el canal vaginal, no se llevan a cabo, por lo que el feto presenta dificultad respiratoria al nacer= .

En el estudio analítico realizado en 25 Centros Obstétricos de Estados Unidos, con alre= dedor de 63180 mujeres incluidas, se intentó un trabajo de parto previo a su ces= área electiva en donde el 18% presentó distrés respiratorio y se concluyó com= o un factor de protección para el recién nacido. Así mismo, en el Hospital NÃ= ºÃ±ez de Perú, se analizaron más de 160 pacientes en las que se realizó un trabaj= o de parto previo a la cesárea programada, en donde la frecuencia de distrés respiratorio fue inferior al 30% comparado con aquellas en donde no se les practicó el trabajo de parto por lo que se estableció como un factor de r= iesgo.

La variante mÃ= ¡s frecuente del Síndrome de Distress Respiratorio se describe como la Taquip= nea Transitoria del Recién Nacido (TTRN), patología que se da principalmente = en neonatos a término por retención de líquido a nivel pulmonar que normalm= ente se extrae por las contracciones producidas por la madre en el parto vaginal (Guia Práctica Clinica, 2016; Mancilla & Villanueva, 2016). Shukla & Mittal (2015) lo comprueban en su estudio retrospectivo realizado en el año 2015 en Karnataka-India, donde de un total de 134 neonatos nacidos por cesárea electiva, la incidencia de TTRN fue del 15,8% y del 6,3% en los recién nac= idos de 37 a 38, 6 y ≥39 semanas de gestación respectivamente.

Se señala que= el índice de cesáreas es mayor a nivel del sector privado que en el público= , en especial por petición materna, principalmente por sugerencia por parte del médico, 38,3% de las cesáreas electivas en una revisión realizada en IrÃ= ¡n (Rafiei & Ghare Naz, 2018). 

Es así que la investigación realizada en México aproximadamente el 63% fue realizado de= forma privada (C. Garcíal, 2018), en Brasil cerca de un 72%, y en China , la tasa de cesáreas electivas en sectores privados es mayor al 71%. (Rosenberg & Trevathan, 2018)<= !--[if supportFields]>, sin embargo, en Chile, cerca del 77,8% de la población cree que es de menos riesgo el parto vaginal que la cesárea (Carvajal C & Ralph T, 2018).

Elementos como= la administración de oxitocina y corticoide antes de la realización de una cesárea programa= da, se describen como factores protectores, lo que se indica en la revisión sistemática realizada en el Hospital del Reino Unido por Gazitúa y su col= ega Pérez, además del trabajo de parto, en donde la frecuencia de distrés re= spiratorio fue inferior al 25%.

Al ser un procedimiento quirúrgico, se requiere anestesia que podría ser general o raquídea según sea el caso; se verifica que en la anestesia espinal (la m= ás empleada) hay muy pocas posibilidades de intoxicación farmacéutica y menor cantidad de fármaco se transfiere al feto y no se ha establecido complicac= iones respiratorias fetales (Abdollahpour et al., 2015).

Los resultados del estudio se resumen en la Tabla Nº1:

= Tabla Nº1.- Estudios relacionados con la cesárea electiva como factor de riesgo= para el desarrollo de Distress Respiratorio Neonatal.

 

REFER. BIBLIO.

AUTOR

AÑO

FINALIDAD

FUENTE

CONCLUSIONES

(Hidalgo, 2015)

Hidalgo, A.=

2015=

Determinar los factore= s de riesgo que se asocian al Síndrome de dificultad respiratoria en nacimien= tos por cesárea o vía vaginal.

Estudio analítico, retrospectivo de casos y controles en el Hospital Universitario de Guayaq= uil, 77 pacientes con diagnóstico de distrés respiratorio neonatal.

Se establece que la mortalidad y morbilidad neonatal del Ecuador posee un riesgo de 2,5 en re= cién nacidos por cesárea electiva.

(Bautista, 2018)

Bautista, L. & Izquierdo, C.

2018=

Conocer la prevalencia= de un tipo de SDRN (TTRN) en neonatos nacidos por cesárea y parto vaginal.<= o:p>

Estudio analítico, ca= sos y controles, retrospectivo realizado en el Hospital Vicente Corral Moscoso, retrospectivo en donde participaron 834 neonatos, nacidos por cesárea y = parto vaginal.

La frecuencia de TTRN = es superior a comparación de la bibliografía analizada, se encontraron fac= tores de riesgo como la cesárea electiva.

(Trujillo Angeles, 2018)

Trujillo, W.

2018=

Describir los factores= de riesgo que se asocian al SDRN en nacimientos por cesárea o vía vaginal.=

Estudio analítico, retrospectivo de casos y controles en el Hospital de Ventanilla de 197 neonatos nacidos por cesárea programadas y parto vaginal.

Los factores que se relacionaron al desarrollo de TTRN fueron principalmente la cesárea elec= tiva, género masculino y macrosomía fetal.

(Morales Máximo & Morales Máximo, 2016)

Morales, D.=

2015=

Conocer las complicaci= ones tanto maternas como fetales de la cesárea electiva en comparación con el parto vaginal

Se realizó un estudio descriptivo, tipo comparativo en donde se trabajó con 150 gestantes some= tidas a cesárea electiva y parto vaginal, y su relación con el desarrollo de morbilidad respiratoria neonatal.

Se concluyó que ambas vías, presentan riesgos similares de distrés respiratorio y la decisió= n de su realización depende de la evolución de la madre y el neonato, todo ello= en base a la decisión del médico.

(Céspedes, 2016)

Céspedes, A.

2016=

Indicar la complicaciÃ= ³n SDRN en la cesárea electiva y el parto vaginal

Estudio analítico en = el Hospital Rafael A. Calderón, 396 pacientes sometidas a cesárea electiva= y 1188 a parto vaginal.

Un embarazo >39 sem= anas o a término sometido a parto vaginal es menos riesgoso que el parto vagi= nal, en especial en cuanto a morbilidad respiratoria.

(Nakimuli & Nakubulwa, 2015)

Nakimuli Et al

2015=

Establecer la incidenc= ia y determinantes de la morbilidad neonatal de la cesárea electiva

Estudio analítico, retrospectivo:  25.846 cesáreas electivas en el Hospital de Mulago.

La cesárea electiva se asocia con importantes efectos neonatales y maternos. Se recomienda que l= as cesáreas electivas se realicen después de las 39 semanas de gestación,= y preferiblemente evitar el uso de anestesia general.

(Li et al., 2019)

Zhang, C., Zhang, D., & Li, Y.

2019=

Describir la asociaciÃ= ³n de la cesárea electiva y el desarrollo de dificultad respiratoria neonatal<= o:p>

Meta-análisis de 15 estudios relacionados a la asociación entre cesárea electiva y el riesg= o de neonatal de distrés respiratorio: 8 estudios en América del Norte, 6 es= tudios en Europa y uno en Asia

El desarrollo de dificultad respiratoria neonatal está íntimamente desarrollado con la c= esárea que se realiza de forma programada con una probabilidad hasta de 2,8.

(Benjamin M. Davis, Gle= n F. Rall, 2017)

Beth, A. Et al

2019=

Asociación del trabaj= o de parto con la producción de morbilidad respiratoria en neonatos a términ= o

Se seleccionaron 23 Hospitales de EE. UU., 63.187 gestantes y 10629 sometidas a labor de part= o

El trabajo de parto se asoció con menores probabilidades de Distrés Respiratorio en recién na= cidos entre las 38 y 39 semanas de gestación.

(Abdelazim et al., 2017)

Abdelazim Et al

2017=

Conocer el impacto de = la administración de oxitocina antenatal en la generación de morbilidad respiratoria en neonatos asociado con la cesárea electiva.

965 recién nacidos de >=3D 37 semanas de gestación nacidos por cesárea electiva, en dos gr= upos: expuestos y no expuestos a oxitocina.

La morbilidad respirat= oria neonatal asociada con la cesárea electiva disminuyó significativamente después de la exposición prenatal a la oxitocina. Una reducción signif= icativa

de morbilidad respirat= oria neonatal se lograría si se realizara cesárea electiva=

después de 39 semanas= de gestación.

(Dileep et al., 2015)

Dileep, A., Babar, N., Sadiq, S.

2015=

Comparar la morbilidad respiratoria neonatal en la cesárea electiva.

Estudio retrospectivo = en el Hospital de Karachi en base al historial médico de gestantes sometida= s a cesárea electiva, 196 respectivamente, con y sin administración de dexametasona antenatal.

Se encontraron efectos beneficiosos de la dexametasona profiláctica en la morbilidad respirator= ia neonatal, pero se requieren más estudios prospectivos con un gran tamañ= o de muestra.

(Pirjani, 2018)

Pirjani, R. et al.

2018=

Asociación de la cesÃ= ¡rea electiva y el distrés respiratorio neonatal en gestantes a término=

Estudio prospectivo, analítico en Irán, se estudiaron 4892 pacientes sometidas a cesárea electiva.

Existe mayor riesgo de complicaciones respiratorias en neonatos menores de 39 semanas, por lo qu= e se sugiere realizar el procedimiento en edades > a 39 semanas.

(Petour Gazitúa, 2015)

Gazitúa, F. & Pé= rez, J.

2015=

Uso de corticoides ant= es del parto para la reducción de la morbilidad respiratoria en cesárea el= ectiva

Se seleccionaron 2 estudios, en donde se administró corticoide antenatal<= /p>

El uso de corticoides = en cesáreas programadas en neonatos a término reduce la frecuencia de SDRN= .

(Shraddha K. Shetty, 2015)

Shraddha, S. & She= tty, A.

2015=

Asociar la aparición morbilidad neonatal con la cesárea electiva.

Estudio retrospectivo = en el Departamento de G-O de Karnataka-India, 1739 nacimientos por vía vagi= nal y 1151 por cesárea electiva.

Los recién nacidos por cesárea electiva a las 37 a 38,6 semanas de gestación tienen un mayor r= iesgo de

desarrollar morbilidad respiratoria a comparación con los niños nacidos después de las 39 sem= anas. La morbilidad respiratoria puede ser

reducido al retrasar la cesárea electiva hasta las 39 semanas de gestación.

(Rafiei & Ghare Naz, 2018)

Rafiei Et al

2018=

Determinar la prevalen= cia, causas y complicaciones de la operación cesárea en Irán

Se consideraron cuaren= ta y un artículos, el número total de la muestra fue 197514 mujeres embaraza= das con una media

edad de 26,72 años

La prevalencia de cesÃ= ¡reas programadas en Irán a nivel privado es mucho más alta de lo que la OMS<= o:p>

recomienda. Es fundamental, para disminuir tal fenómeno, concientizar a las madres acer= ca

de los riesgos del par= to por cesárea.

Fuente:  Bibliografías consultadas

Elaborado por: Propia Autor= ía

 

DISCUSIÓN

14 artículos fueron considerados con respecto a ciertos criterios y = se incluyeron en la revisión sistemática para realizar un estudio comparativ= o de la siguiente forma:

= Gráfico Nº1.- Estrategia de búsqueda de revistas bibliográficas.

<= /span>

Elaborado por: Propia Autoría

A nivel micro podemos basarnos en 2 estudios analíticos, retrospecti= vos de casos y controles realizados a nivel Nacional, Cuenca y Guayaquil: se encontró que la cesárea electiva se asocia de manera significativa con el desarrollo de Síndrome de Distress Respiratorio en el neonato, presentando hasta 2,7 y 2,4 veces más (valor de p inferior a 0,05), respectivamente, de probabilidad a comparación del parto vaginal (Bautista, 2018; Hidalgo, 2015).

Países latinoamericanos como Perú concuerdan con los anteriores enunciados. 2 estudios analíticos, retrospectivos de casos y controles: el primero incluyó 197 neonatos nacidos en edades gestacionales mayores a las= 39 semanas por cesárea programada, 48,2% presentaron taquipnea transitoria del recién nacido con un OR de 4.1 y además se observó mayor predisposición= en el sexo masculino con un OR (razón de momios) de 8.1 (Trujillo Angel= es, 2018). No obstante, el segundo estudio incluyó 150 pacientes sometidas a cesárea electiva, más del 13 por ciento presentaron complicaciones respiratorias como taquipnea transitoria del recién nacido (68%), enfermedad de membrana hialina (32%), pero el 12% de nacidos por par= to vaginal también desarrollaron complicaciones respiratorias, por lo que establece que ambas vías de parto presentan el mismo riesgo (Morales Máxim= o & Morales Máximo, 2016).

En Costa Rica, el estudio retrospectivo, analítico de cohorte transv= ersal relata similitud en el desarrollo de dificultad respiratoria en neonatos nacidos por cesárea programada; trescientas noventa y seis pacientes expue= stas al factor de riesgo, el 9.6% de neonatos presentaron distrés respiratorio = con un riesgo relativo de 2.5 (valor de p de 0.05), igual que lo descrito en Ecuador (Céspedes, 201= 6).

En Uganda, país de Ãfrica, se demostró en una investigación prosp= ectiva similar a las anteriores, 116 recién nacidos por cesárea electiva de un t= otal 5760 partos, quienes presentaron complicaciones neonatales, el 58% fue por dificultad respiratoria con un OR de 3.01 y valor de P de 0.035 (Nakimuli & Nakubulwa, 2015).

Un meta-análisis realizado en el año 2019, evaluaron 15 estudios relacionados a la asociación entre cesárea electiva y el riesgo de neonat= al de distrés respiratorio, se realizaron 8 estudios en América del Norte, 6 es= tudios en Europa y uno en Asia. En cuanto al diseño del estudio, hubo 11 estudios= de cohorte y 4 estudios de casos y controles. El OR combinado del riesgo de SDR neonatal asociado con cesárea electiva fue de 2.38, valor de P inferior a = 0.05 (Li et al., 201= 9).

El mecanismo principal es la ausencia de un trabajo de parto verdader= o. En el  análisis realizado en distint= os centros obstétricos de Estados Unidos, donde participaron 10560 gestantes,= 2% (21 pacientes) en quienes se realizó cesárea programada por diagnóstico = de cesárea anterior: en 6 pacientes se probó trabajo de parto previo al acto quirúrgico y el 10% de neonatos presentaron distrés respiratorio, en comparación del 100% de neonatos en donde no se realizó un trabajo de par= to, presentando un OR de 2.91 (valor de P de 0.032), es decir, la labor de part= o es un factor protector para el desarrollo de distrés respiratorio en neonatos nacidos por cesárea programada (Benjamin M. Da= vis, Glen F. Rall, 2017).

Un estudio observacional, retrospectivo realizado en Kuwait- País del Medio Oriente, se analizaron 65 neonatos nacidos por cesárea electiva que presentaron Taquipnea Transitoria del Recién Nacido (TTRN), en cuyas madre= s se administró oxitocina: el índice de dificultad respiratoria fue mayor en a= quellas en donde no se administró la hormona (8 veces más de probabilidad de pres= entar morbilidad respiratoria) (Abdelazim et a= l., 2017).

Otro factor descrito como protector para evitar el desarrollo del Síndrome de Dificult= ad Respiratoria son los corticoides antenatales detallado en el artículo real= izado en el Hospital de Pakistán. Se incluyeron 196 neonatos nacidos por cesárea programada; el 6% presentó taquipnea transitoria del recién nacido, el 10= % en neonatos en los que se administró corticoides antenatales 24 horas previos= , y el 90% de los que no se les administró, por lo tanto, los neonatos que no = son expuestos a dosis de corticoide antes de su nacimiento tienen un riesgo de = 4,2 veces más de tener dificultad respiratoria en comparación de los expuesto= s al factor protector (valor de P de 0.05) (Dileep et al., 2015).

La cesárea programada es un procedimiento que se debe realizar según normas y protoco= los, y si se efectúa en condiciones óptimas es considerado como seguro, pero s= i se realiza sin indicación médica que se justifique se obtendría mayores rie= sgos que beneficios (María & Alonso, 2015; Schmitz et al., 2017= ). En países como México, en donde se observó que el mayor índice de cesá= reas electivas se realizó de forma privada por petición materna, y el riesgo n= eonatal de padecer dificultad respiratoria es fue de 3 veces más a comparación de países desarrollados como China y Estados Unidos.

Se ha registra= do un mayor número de casos de TTRN en el sector público en países como Ecu= ador ya que en su mayoría se realiza a partir de las 39 semanas de gestación, seg= ún lo establecido en el Ministerio de Salud (Bautista, 2018; Hidalgo, 2015; MSP, 2015).

En la investigación prospectiva de casos y controles realizado en Irán, se estu= diaron 4892 pacientes sometidas a cesárea electiva, 2086 de los neonatos presenta= ron dificultad respiratoria con un OR de 2.9 (valor de p de 0.032), en donde el= 52% oscilaban en edades gestacionales entre 38 a 38.6 y el 48% de 39 semanas, a= su vez el 76% del total presentó TTRN y el 24% presentó Enfermedad de Membra= na Hialina (Pirjani, 2018).

De igual forma= , en la revisión sistemática de 452 mujeres con intervención por cesárea pro= gramada, en la ciudad de Suez de Egipto, se evidenció que el 23.2% tuvo distrés respiratorio de los cuales el 19.6% con diagnóstico de taquipnea transitor= ia del recién nacidos en menores de 39 semanas, Riesgo relativo de 1.4 y valo= r de P de 0.02 (Petour Gazitúa, 2015). Similar resultado se obtuvo en la India, Shraddha & Anil establecieron = que existe un riesgo de 2.82 de probabilidad de que edades gestacionales entre = 37 y 38 semanas presenten distrés respiratorio neonatal con su variante más co= mún la TTRN, valor de P de menor a 0.05.

Por el contrar= io, Rafiei & Ghare Naz (2018) afirman en su estudio que el motivo principal del incremento de cesáreas e= s a nivel privado, por sugerencia médica y al realizarse antes de las 38 seman= as de gestación, son prevalentes patologías como la Enfermedad de Membrana Hial= ina en un 20% superior a la TTRN e inferior a un 5% al Síndrome de Aspiración Me= conial

Por lo tanto, se sugiere la administración de corticoides antenatales, probar el trabajo de parto en pacientes con cesár= eas anteriores con administración de oxitocina, y realizar dicho procedimiento= en edades gestacionales superiores a las 39 semanas, ya que se ha observado una disminución notable de morbilidad respiratoria en recién nacidos hasta de= l 67% (Abdelazim et al., 2017; Benjamin M. Davis, Glen= F. Rall, 2017).

El mayor núme= ro de cesáreas electivas se realiza con anestesia raquídea, lo cual no represen= ta un riesgo de morbi-mortalidad fetal, pero su combinación con benzodiacepinas y opioides podría causar estragos maternos como hipotensión, náusea y vóm= ito (Abdollahpour et al., 2015).

CONCLUSIONES

·      =    De acuerdo a la revisión bibliográfica realiza= da se concluye que las cesáreas electivas, en especial en el sector privado, son consideradas como las más realizadas en especial en países subdesarrollad= os como nuestro país con valores superiores al 40%, donde la tasa de natalida= d es una de las más altas en todo el mundo.

·      =    A su vez, al tratarse de un proceso quirúrgico = que puede traer consigo beneficios tanto para la madre como para el neonato, ocasiona complicaciones, entre las más frecuentes el distrés respiratorio neonatal, el cual representa un riesgo hasta 3 veces mayor comparado al par= to por vía vaginal, por lo que se determina como factor de riesgo. En el Ecua= dor se estimó que existe un riesgo de 2,5 de presentar distrés respiratorio en recién nacidos por cesárea electiva.

·      =    El parto por cesárea programada se realiza en su mayoría en embarazos a término. La entidad más frecuente se describe com= o la TTRN, patología que se podría prevenir con una prueba de trabajo de parto previo en pacientes con antecedentes de cesárea anterior, administración = de oxitocina y corticoides antenatales según protocolos.

 

 

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 PARA CIT= AR EL ARTÃCULO INDEXADO.

 

 

Moncayo Rivera, D. M., Moncayo Rivera, C. M., Serpa Calderón, J. M., & Chacha = Suscal= , N. R. (2021). Cesárea Electiva como Factor de Riesgo Asociado al Síndrome= de Distress Respiratorio Neonatal. Anatomía Digital, 4(= 1), 225-243. https://doi.org/10.33262/anatomiadigital.v4i1.1561

 

 


 

 

 

El artículo que se publica es de exclusiva responsabilidad de los autores y no necesariamente reflejan el pensamiento de la Revi= sta Anatomía Digital.

 

El artículo queda en propiedad de la revista y, por tanto, su publicación pa= rcial y/o total en otro medio tiene que ser autorizado por el director de la Revista Anatomía Digital.

 

 

 

 



[1] Un= iversidad Católica de Cuenca, Facultad de Medicina, Cuenca, Ecuador, email: <= span lang=3DES>diana.moncayo090997@gmail.com. <= /span>https://orcid.o= rg/0000-0002-3364-8052. .

[2] Mi= nisterio de salud pública, Cuenca, Hospital Vicente Corral Moscoso, christianmoncayo487@gmail.com. <= /span>https://orcid.org/0000-0002-4734-7314

[3]  Ministerio de salud pública, Cuenca, D= istrito de salud, justa0000@gmail.com, https://orcid.org/0000-0002-2099-5100  

[4] Mi= nisterio de salud pública, Cuenca, Hospital Vicente Corral Moscoso, ricardocsmed93@= gmail.com.  https://orcid.org/000= 0-0002-2096-5100  

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Salud & Educación                  =                                      Â=  Â Â Â Â                  =                                      Â=  Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â Â  Página 2

 

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