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Cambios morfológicos e= n el sistema estomatognático del adulto mayor, aspectos de interés para Atenci= ón Estomatológica Integral

 

 

Morphological changes in the stomatognathic system= of the elderly, aspects of interest for Comprehensive Stomatological Care

 

Mirian Marlen Rodríguez   Casas[1], = Larisa Hernández Falcón2,  María Isabel Garay Crespo3& Lissette Castillo Mateu4

 

Recibido: 05-09-2020 / Revisado: 29-1= 0-2020 /Aceptado: 19-11-2020/ Publicado: 02-01-2021

DOI: https://doi.o= rg/10.33262/anatomiadigital.v4i1.1477

 

Abstract.

 

As man ages, modifications occur in the structures that make up the massive facial skull. Health professionals need to have an accurate perception of the transformations that occur and the impact they have for= the elderly in the prevention and treatment of diseases in the oral cavity. In order to describe the physiological changes of the stomatognathic apparat= us in the elderly, to contribute to a higher quality of dental care, a bibliographic review of the main investigations processed in the Medline = Complete, Scielo and Infomed databases was carried out. These age-related modificat= ions occur in all components of the stomatognathic system: muscles, teeth, periodontium, oral mucosa, tongue, salivary glands, jaw bones, and temporomandibular joint. They may not all be present, which depends on various genetic factors hereditary and organic, environmental, nutritiona= l, economic and social. These variations should be taken into account to differentiate them from pathological lesions of local or systemic origin,= which can develop in older adults.It is the function of the comprehensive gener= al stomatologist, to help the elderly maintain good oral health by identifyi= ng these normal changes typical of age, to offer them a better quality of li= fe.

 

Keywords:Physiological changes, older adult, stomatogna= thic apparatus, oral cavity.<= /span>

 

Resumen.

 

A medida que el hombre envejece se producen modificaciones en las estructuras que conforman el macizo cráneo facial.= Los profesionales de la salud necesitan tener una percepción exacta sobre las transformaciones que ocurren y el impacto que tienen para los ancianos en= la prevención y tratamiento de las enfermedades en la cavidad bucal. Con el objetivo de describir los cambios fisiológicos del aparato estomatognát= ico en el adulto mayor, para contribuir a una mayor calidad en la atención estomatológica, se realizó una revisión bibliográfica de las principa= les investigaciones    procesadas = en las bases de datos Medline Complete, Scielo e Infomed. Estas modificaciones relacionadas con la edad se producen en todos los componentes del sistema estomatognático: músculos, dientes, periodonto, mucosa oral, lengua, glándulas salivares, huesos maxilares y articulación temporomandibular. Pueden no estar todas presentes, lo que depende de diversos factores genéticos hereditarios y orgánicos, ambientales, nutricionales, económ= icos y sociales. Estas variaciones se deben tener en cuenta para diferenciarlas = de lesiones patológicas de origen local o sistémico, que pueden desarrolla= rse en las personas adultas mayores Es función del estomatólogo general integr= al, ayudar a los ancianos a mantener una buena salud bucal mediante la identificación de estos cambios normales propios de la edad, para ofrece= rles una mejor calidad de vida.

Palabras claves: Cambios fisiológicos, adulto mayor, aparato estomatognático, ca= vidad bucal.

Introducción.=

Lo= grar un incremento de la esperanza de vida es un anhelo de todo ser humano, y es considerado un logro en el que mucho ha aportado el desarrollo de la cienci= a. Martínez (2016) afirma " La vejez, si no es un divino tesoro, resulta= un preciado don que en la actualidad disfrutan más de 600 millones de personas mayores de 60 años en el planeta"

Go= nzález (2015) expresa que esta etapa de la vida se define por cambios y transformaciones producidas por la interrelación entre varios factores, entre ellos tenemos= los factores genéticos y ambientales, asociados a factores de riesgo. En la actualidad se aprecia que muchas personas sobrepasan las barreras cronológ= icas, convirtiéndose así el envejecimiento en reto para las sociedades modernas= , de la cual Cuba no es la excepción. Así, el proceso de envejecimiento de la población cubana mantiene un ritmo acelerado, hasta el punto de que ya la = Isla es, después de Uruguay, el segundo país más envejecido de América Latin= a y el Caribe†(Creagt y Benítez, 2015).

Se= ha podido evidenciar que este proceso es la sucesión de cambios morfológicos, psicológicos, funcionales, y bioquímicos, que resulta del paso del tiempo= sobre los organismos vivos, existiendo una disminución gradual de la capacidad de reserva del organismo ante los cambios, siendo este proceso continuo, inici= ándose con el nacimiento y desarrollándose a lo largo de la vida (Villafuerte,201= 7). Investigaciones realizadas describen, como con el paso del tiempo se afectan todos los niveles de organización biológica, desde las moléculas hasta l= os sistemas fisiológicos (Vélez, = 2019).

En este siglo la población cubana tie= ne una vida más prolongada, como resultado de los grandes avances en el campo= de la salud, cuyos servicios disponen de una cobertura total. Cuba sostiene co= mo premisa brindar particular atención a la implementación de estrategias en= todos los sectores de la sociedad, para enfrentar los eminentes niveles de envejecimiento de la población, así como optimizar la atención integral = y la calidad de los servicios que se brindan para lograr el bienestar de la población, lo que nos impone un gran desafío en la investigación, la doc= encia y la asistencia médica de los adultos mayores (Benítez y González, 2015).<= o:p>

 

Con el propósito de brindar una mayor= calidad en la Atención Primaria de Salud, se forman profesionales en la Especialid= ad de Estomatología General Integral (EGI) competentes para el desempeño asiste= ncial del paciente y la comunidad geriátrica, basado en estudios científicos y tecnológicos actualizados, para el diagnóstico, la prevención y el trata= miento integral de las patologías que puedan estar presentes en la cavidad oral.<= o:p>

 

Ay= mé (2017) enfatiza en su artículo que, para la prevención y tratamiento de las enfermedades en la cavidad bucal en el adulto mayor, es preciso conocer los cambios fisiológicos que se producen en esta etapa de la vida. A medida qu= e el hombre envejece se producen cambios en las estructuras que conforman el sis= tema estomatognático por lo que los profesionales de la salud necesitan tener u= na percepción exacta sobre estos cambios y el impacto que tienen para los ancianos.

En= la ancianidad las trasformaciones fisiológicas que se producen en la orofarin= ge influyen en la salud general, ya que la cavidad bucal interviene en diferentes funci= ones como la fonética, la masticación, deglución de los alimentos y en la est= ética, por lo tanto, en la autoestima (Martínez, 2016).Los cambios biológicos y psicológicos que se presentan en esta etapa de la vida, sumados a las enfermedades de la cavidad bucal comprometen el bienestar psicosocial del paciente afectando su calidad de vida(Gómez, 2019).

Las variaciones  morfológicas y funci= onales que tienen lugar en la cavidad bucal con la edad, forman parte del envejecimiento general del organismo, como el oscurecimiento y desgaste de = los dientes, en cambio, otros pueden ser resultado de la acción de enfermedade= s, o por consumo de medicamentos, estos cambios bucales relacionados con la edad pueden tener dos orígenes: como resultado del envejecimiento propiamente d= icho o por la acción de factores fisiológicos que no provocan enfermedad, pero inducen cambios bioquímicos funcionales y estructurales (Benítez,2015).

La= place (2013) alude a que en esta etapa de la vida hay un aumento de la aparición de afecciones estomatológicas, entre ellas las más comunes son en los tejidos periodontales, las aftas, la candidiasis, la disfunción masticatoria, y el cáncer bucal. Es muy frecuente que los ancianos dejen de asistir al estomatólogo para realizarse revisiones, pues refieren que ya no tienen di= entes y no es por tanto necesario, salvo que se desajuste su prótesis; no obstan= te, para la prevención de las afecciones de la cavidad bucal es necesarios ten= er una serie de cuidados que van desde un buen cepillado hasta la visita al estomatólogo cada seis meses.

Las autoras de ese estudio estiman que la mayoría de las investigaciones reali= zadas sobre los adultos mayores tratan sobre las causas, factores de riesgo, y evolución de las diversas enfermedades que suelen hacerse presentes en est= as edades, sin embargo, es de gran importancia tener una percepción exacta so= bre las transformaciones que ocurren en el macizo cráneo facial relacionados con el envejecimiento, de ahí que el objetivo de este estudio es describir los ca= mbios fisiológicos del aparato estomatognático del adulto mayor para contribuir= a una mayor calidad en la atención estomatológica integral.

Metodologia.=

Sobre estos aspectos se realizó una revisi= ón sistemática en Inglés y Español de los principales artículos publicados= en las bases de datos Medline Complete, Scielo, PubMed, e Infomed, para lo cual se utilizaron los descriptores: cambios fisiológicos, adulto mayor, aparato e= stomatognático, cavidad bucal. Se incluyó en esta revisión las variaciones clínicas que = se deben tomar siempre en cuenta para una mejor calidad en la atención estomatológica al adulto mayor. Las referencias de los artículos recupera= dos por la búsqueda electrónica fueron investigadas en otros artículos potencialmente elegibles.

 <= /o:p>

Resultados= .

Los cambios relacionados con la edad se producen en todos los componentes del sistema estomatognático: músculos, dientes, periodonto, m= ucosa oral, lengua, glándulas salivares, huesos maxilares y articulación temporomandibular.

Para identificar las variaciones que aparecen en los tejidos bucales y se relaci= onan al envejecimiento es útil describirlos a nivel de las siguientes estructur= as: facial y bucal.

Cambio= s a nivel facial:

A nivel facial y con el paso de los años se presentan una serie de transformaciones que comienzan con la presencia de arrugas frontales e interciliares y se van extendiendo con el transcurso del tiempo a nivel del cuello. El tercio superior de la cara se agranda provocado por la caída del pelo, en el tercio medio facial se puede observar la formación de bolsas palpebrales= , además en la zona de las mejillas se presenta una concavidad por la acentu= ación de la prominencia de los pómulos, mientras que el tercio inferior de la ca= ra se reduce por la atrofia de los rebordes alveolare= s, que va acompañado de pérdida de altura facial (Castiñeira, 2018).

Se= ha podido evidenciar que los músculos masticatorios y la piel pierden despué= s de los 30 a 65 años el 20 % de su actividad muscular. El tejido facial dismin= uye su elasticidad y fuerza debido a la deshidratación y hay un aumento del te= jido fibroso. La debilidad de la musculatura es un aspecto reconocido en el envejecimiento fisiológico, debido a que este tejido se atrofia lentamente= y dicha involución se manifiesta en un aumento de la fragilidad y dificultad gradual para la realización de pequeños esfuerzos, con disminución de la actividad muscular (Sáez,2007). Otros estudios enfatizan que el envejecimiento de la musculatura del sistema est= omatognático puede estar en correspondencia con el agotamiento de las células madres y = el remodelado vascular, que puede ser el responsable en los cambios de la func= ión muscular (Torrecilla-Venegas, 2020).

En la literatura consultada se describe que la presencia de= arrugas en los labios (arrugas radiales), la acentuación del surco naso geniano, así como la disminución de la tonici= dad de los músculos faciales, acompañado de la ausencia de tejido adiposo deja m= arcar las estructuras óseas que se encuentran bajo la piel, originando la facie característica del anciano (Azañe= ro, 2018).

Cambios a nivel bucal:

En= la cavidad bucal se presentan cambios con el envejecimiento, al igual que en t= odos los órganos y sistemas del cuerpo humano.

-D= ientes.

Desde que los dientes erupcionan ocurren una serie de cambios en su estructura, que están relacionados con el paso del tiempo y son el resulta= do de su función y de los factores presentes en la cavidad bucal como: los hábi= tos, la alimentación y la higiene bucal.

MÃ= ©ndez (2018) plantea que los pacientes de la tercera edad presentan cambios en sus estructuras dentales de origen fisiológico dentro de los cuales el cambio = de color y el desgaste dental son los más prevalentes. Los dientes cambian de forma, tamaño, posición, y color por modificación de los tejidos dentarios: debido al incremento o reducción de sustancias inorgánicas y orgánicas, o por la acción de factores presente= s en el medio bucal: erosión, atrición, caries, enfermedad periodontal, pérdida = de dientes, etc. (Sáez, 2007).

Se= gún Torrecilla-Venegas (2020) el esmalte como resultado de la mastic= ación sufre un desgaste natural sin provocar molestia, este tejido se torna opaco haciendo que se vea de color mate, sin brillo y más oscuros. Los di= entes disminuyen su sensibilidad debido a la formación de dentina reparativa, reduciendo el espacio para las fibrillas de Tomes, y continuando su calcificación, al inverso de lo que sucede en los tejidos óseos, estos cambios generan que las piezas dentarias se vu= elvan más frágiles por aumento de la mineralización dentinaria. La pulpa dental se retrae por la producción de dentina secundaria, con lo cual dism= inuye la sensibilidad dolorosa. Esto contribuye a aumentar la variación de los c= uadros que caracterizan las afecciones bucales en la clínica geriátrica.

Ga= rcía (2016) refiere en su estudio que los dientes debido a la carga oclusal a la que es= tán sometidos a lo largo de la vida, sus tejidos de soporte o periodonto tiende= a engrosarse y retraerse, provocando generalmente una mayor exposición de la= superficie de los dientes al medio bucal.

-<= /span>Tejido Periodontal.

La encía se torna de color rosa pálido por la disminución de la circulación sanguínea en ese tejido, producto de la obturación de los capilares submu= cosos (Torrecilla-Venegas, 2020). Además, S= áez (2007) plantea que se observa la pérdida del punteado, presenta un aspecto fibros= o y la capa queratinizada disminuye o se pierde.

El ligamento periodontal tiende a ensancharse en los ancianos, probablemente por una inflamación crónica del ligamento, pues es uno de los componentes del periodonto de inserción. Las variaciones en el ligamento periodontal y la producción de dentina secunda= ria, reduce la sensibilidad dolorosa, por lo cual, los ancianos pueden no referir dolor, aun presentando un estado de salud bucal deficiente (García, 2016). Según San Martin (2002) radiográficamente el ligamento periodontal con el envejecimiento disminuye el espacio periodontal, ocasionando la unión del diente al hueso alveolar por la aposición de cemento secundario.

-Mucosa bucal:

En este tejido se presentan cambios progresivos, que hace a la mucosa bucal mÃ= ¡s vulnerable a las lesiones y procesos infecciosos, la misma se vuelve más f= ina, lisa y de   aspecto edematoso, ha= y pérdida de la elasticidad y del punteado, debido a cambios en el epitelio y tejido conectivo.

La mucosa de las encías y las que cubre el paladar duro recibe el nombre de m= ucosa masticatoria y están preparadas para soportar presiones y fricciones en la= masticación. La mucosa de los labios, carrillos, paladar blando, piso de boca, y superfi= cie ventrolingual, su estructura le permite desplazarse y distenderse durante l= as diferentes funciones en las que participan y están cubiertas por una mucosa denominada mucosa de revestimiento (García, 2016).

Azañero (2018) resume = que la mucosa oral puede ser queratinizada o no queratinizada dependiendo de la re= gión y de su función. La queratina es una proteína fibrosa que opera como una defensa contra la penetración de infecciones. Clínicamen= te el signo más frecuente de envejecimiento de la mucosa bucal es el incremento = de los gránulos de Fordyce, los que se identifican como pequeñas pápulas amarillentas asintomáticas.

 

-Lengua

Es un órgano formado por 17 músculos, su superficie dorsal está revestida p= or una mucosa denominada especializada que tiene cuatro tipos de papilas, tres de = las cuales presentan los corpúsculos gustativos que identifican los diferentes sabores. En los bordes laterales de la raíz de la lengua se encuentran las papilas foliadas, que con frecuencia se hipertrofian con la edad (T= orrecilla-Venegas, 2020).

Con el envejecimiento, en la lengua se presenta una atrofia del epitelio superficial, siendo a nivel del dorso donde con mayor frecuencia se observa= , la misma presenta un aspecto liso con reducción de papilas filiformes,= de tal manera que el sentido del gusto disminuye ocasionando que las person= as mayores sientan insípidos sus alimentos (Azañero, 2018).

-Glándulas salivales:=

Se= ha descrito en los ancianos una reducción del par= énquima de las glándulas salivales, de un 30 al 60% del espesor acinar en las glá= ndulas mayores. Los acinos son sustituidos por tejido adiposo y hay un aumento del tejido fibroso. En el sistema ductal se produce dilatación de conductos ex= tra lobulares, así como cambios degenerativos. Estos cambios no solo están presentes en la glándula submandibular, donde hasta= la mitad de los acinos pueden perderse desde la juventud hasta la vejez, sino también, en la glándula sublingual, en la parótida y en las glándulas s= alivales menores. La contribución de cada glándula al volu= men de secreción salival no es constante y cambia en estado de reposo o de forma estimulada (García, 2016).

La saliva como fluido corporal que protege= la salud bucal, participa en diversas funciones: el inicio de la digestión de= los alimentos, la lubricación del bolo alimenticio, la degustación, la deglución e inte= rviene en la dicción, son demasiadas funciones en las que participa la saliva, si falla, se van a afectar directamente varias funciones básicas en el equili= brio bucodental. La disminución de la cantidad de saliva es una demanda frecuente de consulta = de los adultos mayores, la cual es adjudicada a la reducción del parénquima glandular. Sin embargo, como el proceso de en= vejecimiento es considerado normal, se produce atrofia de las glándulas salivales mayor= es, que finalmente se traduce en un incremento de tejido fibroso y acumulación= de tejido adiposo intercelular, desencadenando una disminución progresiva del flujo salival con alteraciones en el período de vaciamiento = (San Martin, 2002).

 

Las investigaciones odontológicas establecen que existe una disminución en la producción de saliva relacionada con la edad, así como, alteraciones en l= as proteínas antimicrobianas presentes. Las histatinas, que tienen efecto ant= icandidiásico, están particularmente deprimidas (Laplace, 2013).

-Articulación temporomandibular

La articulación temporomandibular (ATM), es la articulación formada por la p= arte superior de la mandíbula y el hueso temporal del cráneo, la cual funciona= como una bisagra para abrir y cerrar la boca. Para poder realizar el diagnóstic= o y tratamiento de los trastornos témporomandibulares (TTM) es necesario conocer las estructuras principales   que=    integran   el   sistema estomatognático (SE) y las variaciones que ocurren con la edad. Caracterizándose por cambios degenerativos aun sin tener manifestaciones clínicas, ni prese= ntar una relación lineal entre la edad y los cambios de la morfología condilar= , ex= istiendo discrepancias del complejo disco-condilar, acompañado de remodelación de = las estructuras articulares (García, 2016).

Re= fiere San Martin (2002) que en la ATM con el paso de los años hay una mayor laxitud = en los movimientos articulares, debido a que su actividad funcional depende de= la información propioceptiva que provienen de los músculos, de los ligamento= s y de las terminaciones nerviosas de la articulación, así como del ligamento periodontal y la mucosa bucal. En la ancianidad la actividad propioceptiva = está reducida y esto produce una disminución del control de los movimientos de = la articulación.

Ga= rcía (2016) expresa en su estudio que la ATM se torna susceptible a los cambios degenerativos debido al paso de los años, observándose radiográficamente= variaciones como: erosiones y alteración de la forma de las superficies articulares, disminución del tamaño del cóndilo mandibular, una mayor posibilidad de perforación del disco articular, osteoporosis, alteraciones de los espacios articulares y discrepancias del complejo discocondilar.

 -Hueso alveolar

En su investigación Sáez(2007)destaca que el hueso alveolar presenta una remodelación contin= ua por su relación con las fuerzas oclusales, debido a que se reducen las fue= rzas oclusales y el hueso alveolar se  reabsorbe disminuyendo su altura y el grosor de su trabéculado; además se puede apr= eciar un adelgazamiento de la cortical con aumento de la porosidad, produciéndose esclerosis ósea, como consecuencia de un incremento de la mineralización = de la estructura ósea, que incrementa la dureza y disminuye la elasticidad, con = una gran probabilidad de fractura. Esto explica el relativo aumento de la densi= dad radiográfica de los pacientes en edad avanzada.

Ot= ro estudio señala que los cambios microscópicos de la matriz ósea y de su composición química, afectan la resistencia del tejido óseo y en la cavi= dad bucal se presentan en un aumento de la pérdida dental en los ancianos dent= ados o la reabsorción del reborde en los edentes (Laplace, 2013).

Los autores de esta revisión coinciden con la evidencia científica en cuanto = a los cambios que se producen en los tejidos que forman parte del sistema estomatognático y le atribuyen un importante papel al envejecimiento, sien= do necesario que el odontólogo = esté actualizado de todos los mecanismos involucrados en este proceso.<= /span>

Los cambios fisiológicos que se han descritos en nuestra investigación pueden= estar presentes en mayor o menor medida en los adultos mayores, lo cual va a depe= nder de diversos factores como son: los hereditarios, orgánicos, nutricionales, ambientales, económicos y sociales. Se debe tener en cuenta que cada indiv= iduo presenta sus propias particularidades.

 

Conclusiones.

·      =    L= os cambios fisiológicos que ocurren en los tejidos del sistema estomatognáti= co asociados a la ancianidad, se presentan a nivel estructural, bioquímico y = en sus mecanismos de defensa frente a la agresión de carácter físico, quím= ico y biológico, los cuales son considerados normales de acuerdo a la edad. Pued= en no estar todos presentes, lo que depende de diversos factores genéticos: hereditarios y orgánicos, ambientales, nutricionales, económicos y social= es.

·      =    E= stas variaciones se deben tener en cuenta para diferenciarlas de lesiones patológicas de origen local o sistémico, que pueden desarrollarse en las personas adultas mayores. El odontólogo = debe tener una percepción exacta de los cambios fisiológicos que ocurren en este pro= ceso de envejecimiento y que no se presentan por igual en los ancianos, para contribuir a una mayor calidad en la atención estomatológica integral.

=  

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Velázquez-Olmedo, L. B., Ortíz-Barri= os, L. B., Cervantes-Velázquez, A., Cárdenas-Bahena, Ã., García-Peña, C., &am= p; Sánchez-García, S. (2014). Calidad de vida relacionada con la salud oral = en adultos mayores. Instrumentos de evaluación. Revista Médica del Instit= uto Mexicano del Seguro Social, 52(4), 448-456.

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Laplace Pérez, Beatriz de las N, Legr= á Matos, Sara María, Fernández Laplace, Josué, Quiñones Márquez, Dinorah= , Piña Suárez, Lizzy, & Castellanos Almestoy, Lourdes. (2013). Enfermedades bucales en el adulto mayor. Correo Científico Médico, 17(4), 477-488. Recuperado en 16 de julio de 2019, de http://scielo.sld.cu/scielo.php?script=3Dsci_arttext&pid=3DS1560-438120= 13000400008&lng=3Des&tlng=3Des.

San Martín, C., Villanueva Maffei, J., &Labraña Pascual, G. (2002). Cambios del sistema estomatognático en el Paciente Adulto Mayor (Parte II).

 

 

 

PARA CITAR EL ARTÃCULO INDEXADO.

 

 

Rodríguez Casas, M. M., Hernández Falcón, L., Garay Crespo, M. I., & Castillo M= ateu, L. (2021). Cambios morfológicos en el sistema estomatognático del adulto = mayor, aspectos de interés para Atención Estomatológica Integral. Anatomía Dig= ital, 4(1), 6-16. https://doi.org/10.33262/anatomiadigital.v4i1.1477

 

 


 

 

 

 

El artículo= que se publica es de exclusiva responsabilidad de los autores y no necesariamente reflejan el pensamiento de la Revi= sta Anatomía Digital.

 <= /o:p>

El artículo= queda en propiedad de la revista y, por tanto, su publicación parcial y/o total = en otro medio tiene que ser autorizado por el director de la Revista Anatomía Digital.

 <= /o:p>

 

 <= /o:p>

<= o:p> 



[1] Universidad de  Ciencias = Médicas de Matanzas. Cuba. Especialista de 1er Grado en Estomatología General Integral,mmrodriguez.mtz@infomed.sld.cu<= /span>  https://orcid.org/0000-0002-= 2224-4845

<= span class=3DMsoHyperlink> 

<= span class=3DMsoHyperlink>2 <= /span>Universidad de Ciencias Mé= dicas de Matanzas. Cuba. Especialista de 2do Grado en Estomatología General Integral,  lhfalcon.mtz@inf= omed.sld.cu <= span lang=3DES-CO style=3D'font-family:"Times New Roman",serif;mso-ansi-language= :ES-CO; mso-fareast-language:ES-CO;mso-no-proof:yes'>  https://orcid.or= g/0000-0002-0826-3265<= /p>

<= span lang=3DES style=3D'font-family:"Times New Roman",serif'> 

<= sup>3 Universidad de Ciencias Mé= dicas de Matanzas. Cuba. Especialista de 1er Grado en Estomatología General Inte= gral,  garaymmtz@infome= d.sld.cu     https://orcid.or= g/0000-0002-7353-0236<= /p>

<= span lang=3DES style=3D'font-family:"Times New Roman",serif'> 

<= sup>4 Universidad de Ciencias Mé= dicas de Matanzas. Cuba. Especialista de 1er Grado en Estomatología General Integral,  lissettecastillo.mtz@infomed.sld.cu     https://orcid.or= g/0000-0002-0955-1074<= /p>

 

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